Shree Signify Exim Private Limited

Brand Names: Lenalid, Revlimid (widely known brand based on composition)

Composition: Lenalidomide 15 mg

Strength: 15 mg

Manufacturer: Natco Pharma Ltd.

Packaging: Typically available in blister packs containing 10 capsules

Treatment: Multiple myeloma, myelodysplastic syndromes (MDS), mantle cell lymphoma

Product Description:
Lenalid 15 Capsule contains Lenalidomide, an immunomodulatory agent that is primarily used in the treatment of certain types of cancers, including multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma. Lenalidomide works by affecting the immune system to inhibit the growth of cancer cells, promote the destruction of abnormal cells, and reduce the formation of blood vessels that supply tumors.

Common indications for Lenalid 15 Capsule include:

• Multiple Myeloma: Used in combination with other medications to treat multiple myeloma, particularly in patients who have received at least one prior therapy.
• Myelodysplastic Syndromes (MDS): Used to treat certain types of MDS, especially in patients with a specific chromosomal abnormality.
• Mantle Cell Lymphoma: Used in patients whose disease has relapsed or progressed after two prior therapies, including bortezomib.

Dosage and Administration:

• For Adults: The dosage of Lenalid 15 Capsule varies depending on the condition being treated. The exact dosage regimen should be determined by a healthcare provider based on individual patient factors and response to treatment.
• Administration: The capsule should be swallowed whole with water, with or without food. It is important to follow the prescribed schedule and not to break, chew, or open the capsules.

Common side effects of Lenalid 15 Capsule may include:

• Fatigue
• Anemia
• Neutropenia (low white blood cell count)
• Thrombocytopenia (low platelet count)
• Diarrhea
• Rash

Due to the risk of serious side effects, including birth defects, Lenalidomide is subject to special safety monitoring and prescribing programs. Patients should discuss all potential risks and benefits with their healthcare provider.

Packaging:
Lenalid 15 Capsule is typically packaged in blister packs containing 10 capsules, providing a convenient form for daily or cyclical use as prescribed by a healthcare provider.

Lenalid 15 Capsule is a critical medication in the management of certain hematological cancers, offering a targeted approach to treatment that leverages the body's immune system to fight disease. Its use in conditions like multiple myeloma and MDS has significantly improved outcomes for many patients, though it requires careful monitoring and adherence to prescribed safety protocols.

Brand Names: Palnat, Ibrance (widely known brand based on composition)

Composition: Palbociclib 125 mg

Strength: 125 mg

Manufacturer: Natco Pharma Ltd.

Packaging: Typically available in blister packs containing 21 capsules

Treatment: Breast cancer (hormone receptor-positive, HER2-negative)

Product Description:
Palnat 125 Capsule contains Palbociclib, a targeted cancer therapy known as a cyclin-dependent kinase (CDK) 4/6 inhibitor. It is used in combination with hormonal therapies to treat hormone receptor-positive, HER2-negative breast cancer. Palbociclib works by inhibiting the activity of CDK4 and CDK6, which are enzymes that promote cell division. By blocking these enzymes, Palbociclib slows the growth and spread of cancer cells.

Common indications for Palnat 125 Capsule include:

• Breast Cancer: Used in combination with an aromatase inhibitor as the first-line treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in postmenopausal women. It is also used with fulvestrant in patients whose disease has progressed after endocrine therapy.

Dosage and Administration:

• For Adults: The recommended dose is 125 mg taken orally once daily for 21 consecutive days, followed by 7 days off treatment, making up a 28-day cycle.
• Administration: The capsule should be swallowed whole with water, preferably with food. It should not be chewed, crushed, or opened.

Common side effects of Palnat 125 Capsule may include:

• Neutropenia (low white blood cell count)
• Fatigue
• Nausea
• Diarrhea
• Infections
• Stomatitis (inflammation of the mouth)
• Thrombocytopenia (low platelet count)

Patients are advised to undergo regular blood tests to monitor blood cell counts during treatment, as well as to report any signs of infection or unusual symptoms to their healthcare provider immediately.

Packaging:
Palnat 125 Capsule is typically packaged in blister packs containing 21 capsules, which corresponds to one cycle of treatment.

Palnat 125 Capsule is an important medication in the treatment of advanced breast cancer, offering a targeted approach that, when used in combination with hormonal therapies, can help control the disease and improve survival outcomes. Adherence to the prescribed regimen and regular monitoring are essential to maximize the benefits of this therapy while managing potential side effects.

Product Name: Erdanat 3mg/4mg/5mg Tablets

Brand Name: Erdanat, Balversa, Erdaheal

Composition: Erdafitinib (3mg/4mg/5mg)

Manufacturer/Marketer: Natco Pharma

Packaging: To be provided (specify packaging details if available)

Treatment: Urothelial carcinoma (bladder cancer) with FGFR genetic alterations

Product Description: Erdanat Tablets contain Erdafitinib, a targeted therapy that inhibits fibroblast growth factor receptor (FGFR) pathways involved in cancer cell growth. It is used in the treatment of advanced or metastatic urothelial carcinoma with specific FGFR mutations or fusions. This medication helps slow tumor growth and progression by blocking abnormal signaling pathways in cancer cells.

Product Description: Silofast 8mg Capsules contain Silodosin 8mg, a selective alpha-1 adrenergic receptor antagonist that is primarily used to treat symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland in men. By relaxing the muscles in the prostate and bladder neck, Silodosin helps relieve symptoms such as difficulty in urination, a weak urine stream, and frequent or urgent urination, allowing smoother urine flow.

Silofast is highly effective in improving urinary symptoms and quality of life for men with BPH. It specifically targets the alpha-1A receptors in the prostate, minimizing the effect on blood pressure compared to other alpha-blockers. This makes it suitable for older patients or those with comorbidities.

Common side effects include dizziness, retrograde ejaculation (where semen enters the bladder instead of exiting through the penis), and a runny or stuffy nose. It is advised to take the capsule with food to reduce the risk of side effects, and patients should avoid operating heavy machinery or driving until they know how the medication affects them.

Silofast 8mg should be used under medical supervision, and patients are encouraged to consult their healthcare provider if they experience any severe side effects or if their symptoms do not improve. Regular follow-ups may be necessary to monitor the progression of BPH and the effectiveness of the treatment.

Product Name: Cazanat 40 Tablet

Brand Name: Cazanat, Cabometyx, Cabozanib

Composition: Cabozantinib (40mg)

Manufacturer/Marketer: Natco Pharma Ltd

Packaging: To be provided (specify packaging details if available)

Treatment: Kidney cancer, liver cancer, thyroid cancer

Product Description: Cazanat 40 Tablet contains Cabozantinib, a targeted therapy medication used to treat advanced kidney, liver, and thyroid cancers. It works by inhibiting the growth of cancer cells by blocking specific proteins involved in tumor growth and angiogenesis, thereby reducing the spread of the disease

Product Name: Tibsovo 250mg Tablet

Brand Name: Tibsovo, Tibsovo (Ivosidenib), AG-120

Composition: Ivosidenib (250mg)

Manufacturer/Marketer: Servier India Pvt Ltd

Packaging: To be provided (specify packaging details if available)

Treatment: Acute myeloid leukemia (AML) with IDH1 mutation, cholangiocarcinoma (IDH1-mutated)

Product Description: Tibsovo 250mg Tablet contains Ivosidenib, a targeted anticancer medication used for the treatment of IDH1 mutation-positive acute myeloid leukemia and certain cases of cholangiocarcinoma. It works by inhibiting the mutant IDH1 enzyme, helping restore normal cell differentiation and reducing the growth of cancerous cells. This targeted therapy improves disease control while minimizing damage to healthy cells

Pomalid 1/2/4 mg Capsule:

• Brand Names: Pomalid, Pomalyst, Pomalong
• Composition: Pomalidomide (1mg, 2mg, or 4mg)
• Manufacturer/Marketer: Natco Pharma Ltd
• Packaging: Box of 21 capsules
• Treatment: Used for the treatment of multiple myeloma (a type of blood cancer) and other conditions related to cancer.

Product Description:
Pomalid contains Pomalidomide, which is an immunomodulatory agent that helps slow down the growth of cancer cells and boosts the immune system to attack cancer. It is commonly used in patients with multiple myeloma who have not responded well to other treatments.

Popular alternatives to Pomalid include Pomalyst and Pomalong

Brand Names: Bracanat, Lynparza (widely known brand based on composition)

Composition: Olaparib 150 mg

Strength: 150 mg

Manufacturer: Natco Pharma Ltd.

Packaging: Typically available in blister packs containing 14 tablets

Treatment: Ovarian cancer, breast cancer, pancreatic cancer, prostate cancer

Product Description:
Bracanat 150mg Tablet contains Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor used in the treatment of various cancers, particularly those associated with BRCA gene mutations. Olaparib works by blocking the PARP enzyme, which helps repair damaged DNA in cells. By inhibiting this enzyme, Olaparib prevents cancer cells from repairing themselves, leading to their death.

Common indications for Bracanat 150mg Tablet include:

• Ovarian Cancer: Used in the maintenance treatment of adult patients with advanced ovarian cancer who have responded to first-line platinum-based chemotherapy.
• Breast Cancer: Used in the treatment of HER2-negative breast cancer with BRCA1/2 mutations.
• Pancreatic Cancer: Used in the maintenance treatment of BRCA-mutated metastatic pancreatic cancer.
• Prostate Cancer: Used in the treatment of metastatic castration-resistant prostate cancer with BRCA1/2 mutations.

Dosage and Administration:

• For Adults: The usual recommended dose is 300 mg (two 150 mg tablets) taken orally twice daily, for a total daily dose of 600 mg.
• Administration: The tablet should be swallowed whole with water, taken at approximately the same times each day, with or without food. It should not be crushed, chewed, or split.

Common side effects of Bracanat 150mg Tablet may include:

• Nausea
• Fatigue
• Anemia
• Vomiting
• Diarrhea
• Loss of appetite

Regular blood tests and monitoring are essential during treatment to manage potential side effects and adjust the dosage as needed.

Packaging:
Bracanat 150mg Tablet is typically packaged in blister packs containing 14 tablets, designed for a one-week course of treatment when taken as prescribed.

Bracanat 150mg Tablet is a significant advancement in cancer treatment, offering targeted therapy for patients with specific genetic mutations. It plays a crucial role in extending survival and improving the quality of life for patients with certain types of advanced cancers, particularly those associated with BRCA mutations. Regular monitoring and adherence to the prescribed regimen are vital to achieving the best possible outcomes.

Brand Names: Tagrisso (widely known brand based on composition)

Composition: Osimertinib

Strength: 80 mg

Manufacturer: AstraZeneca

Packaging: Typically available in a pack of 30 tablets

Treatment: Non-small cell lung cancer (NSCLC) with specific epidermal growth factor receptor (EGFR) mutations

Product Description:
Tagrisso 80mg Tablet contains Osimertinib, a targeted cancer therapy used in the treatment of non-small cell lung cancer (NSCLC) that has specific mutations in the epidermal growth factor receptor (EGFR). Osimertinib is an EGFR tyrosine kinase inhibitor (TKI) that works by blocking the activity of the mutated EGFR, which drives the growth and spread of cancer cells. It is particularly effective against NSCLC that has developed resistance to other EGFR inhibitors.

Common indications for Tagrisso 80mg Tablet include:

• Cancer Treatment: Used in the management of non-small cell lung cancer (NSCLC) with specific EGFR mutations.

Dosage and Administration:

• For Adults: The typical dose is one 80 mg tablet taken orally once daily. The exact dosage and duration of treatment are determined by the oncologist based on the patient's condition and response to therapy.
• Administration: Tagrisso should be taken with or without food, and at the same time each day.

Common side effects of Tagrisso 80mg Tablet may include:

• Diarrhea
• Rash
• Dry skin
• Stomatitis (inflammation of the mouth)
• Nail changes

Serious side effects can include interstitial lung disease, QT prolongation (a type of heart rhythm problem), and low blood cell counts. Regular monitoring of lung function, heart function, and blood tests is essential during treatment.

Packaging:
Tagrisso 80mg Tablet is typically packaged in a box containing 30 tablets, with each tablet individually sealed to ensure proper dosage and patient safety.

Tagrisso 80mg Tablet is a vital medication in the treatment of non-small cell lung cancer (NSCLC) with specific EGFR mutations. It offers a targeted approach that can significantly improve outcomes for patients with this type of cancer. However, due to its potential for serious side effects, it should be used under the guidance and supervision of an experienced oncologist. Regular monitoring of patient health and response to therapy is crucial during treatment with Osimertinib.

Brand Names: Anaridex, Arimidex

Composition: Anastrozole

Strength: Available in 1 mg tablets

Manufacturer: Healing Pharma.

Packaging: Blister packs of 10 tablets

Treatment: Breast cancer in postmenopausal women

Product Description:
Anaridex (Anastrozole) is a potent aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women. By lowering estrogen levels, Anastrozole helps slow down or stop the growth of cancer cells that rely on estrogen to grow.

Indications:

• Hormone receptor-positive breast cancer in postmenopausal women
• Adjuvant treatment of early breast cancer
• Treatment of advanced breast cancer

Dosage and Administration:
Typically, Anaridex is taken once daily, with or without food, as prescribed by a healthcare provider. The standard dose is 1 mg per day.

Common side effects include:

• Hot flashes
• Fatigue
• Joint pain
• Osteoporosis

Packaging:
Anaridex is available in blister packs containing 10 tablets each.

Product Name: Biovorin 15mg Tablet

Brand Name: Biovorin, Leucovorin, Folinic

Composition: Calcium Leucovorin / Calcium Folinate (15mg)

Manufacturer/Marketer: Zydus Cadila

Packaging: To be provided (specify packaging details if available)

Treatment: Methotrexate toxicity, megaloblastic anemia, colorectal cancer (as adjuvant therapy)

Product Description: Biovorin 15mg Tablet contains Calcium Leucovorin (Calcium Folinate), a medication used to reduce the harmful effects of methotrexate in cancer therapy, treat megaloblastic anemia due to folic acid deficiency, and enhance the efficacy of fluorouracil in colorectal cancer treatment. It works by replenishing folate levels and protecting healthy cells from damage

Product Name: Tucanat 150 Tablet

Brand Name: Tucanat, Tukysa, Tuksan

Composition: Tucatinib (150mg)

Manufacturer/Marketer: Natco Pharma Ltd

Packaging: To be provided (specify packaging details if available)

Treatment: HER2-positive breast cancer (advanced or metastatic)

Product Description: Tucanat 150 Tablet contains Tucatinib, a tyrosine kinase inhibitor used in the treatment of advanced or metastatic HER2-positive breast cancer. Often used in combination with other therapies like trastuzumab and capecitabine, it works by selectively inhibiting the HER2 signaling pathway, slowing cancer cell growth and spread

Generic Nolvadex Tablet is an anti-estrogens. It is used in the treatment of breast cancer. It is also used to reduce the risk of breast cancer in pre- and postmenopausal women with a high risk. This medicine helps to slow down the growth and multiplication of cancer cells.

Generic Nolvadex Tablet is also helpful in the treatment of infertility. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. This medicine is generally taken for 10 to 15 years. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include hot flashes, mood swings, vaginal discharge, vaginal bleeding, nausea, and fluid retention. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some side effects may mean you should inform your doctor immediately include vaginal bleeding, irregular menstrual period, and vaginal discharge. It makes birth control pills less effective, hence use a condom and other preventive measures to avoid pregnancy.

Before taking this medicine, tell your doctor if you are on treatment of infertility or had a blood clot disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check liver function and calcium level in the body.

Generic Nolvadex Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer, both in pre as well as postmenopausal women. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fineova:

• Hot flashes
• Nausea
• Vaginal discharge
• Vaginal bleeding
• Mood swings
• Fluid retention

How To Use Fineova Tablet:

• Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Generic Nolvadex Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Fineova Tablet Works:

• Generic Nolvadex Tablet is a hormone-based medication. It works by binding to estrogen receptors and blocking the effects of estrogen (a natural female hormone) in the breast tissue. This slows down the growth and multiplication of breast cancer cells.

Endace Tablets is used to treat breast cancer. We also have Anorest 40 mg Tablet manufacture by Natco LTD.

Erlonat is a prescription drug and should be used under proper medical guidance and advice. Do not share the medicine with others, since they may be suffering from a problem that is not effectively treated by this drug.

Cycloxan 500 mg Injection:

• Brand Names: Cycloxan, Endoxan, Cytoxan
• Composition: Cyclophosphamide 500 mg
• Strength: 500 mg
• Manufacturer/Marketer: Biochem Pharmaceutical Industries Ltd
• Packaging: Injection vial
• Treatment: Used for treating cancer, including lymphoma, leukemia, breast cancer, and ovarian cancer. It is also used in autoimmune disorders like severe rheumatoid arthritis and lupus.

Product Description:
Cycloxan 500 mg Injection contains Cyclophosphamide, an anti-cancer (antineoplastic) medication from the alkylating agent class. It works by slowing or stopping the growth of cancer cells. It's administered via injection under medical supervision, typically in chemotherapy regimens. Cyclophosphamide is also used to suppress the immune system in cases of severe autoimmune conditions.

Commonly available under brand names such as Cycloxan, Endoxan, and Cytoxan, this drug is widely used for treating various types of cancer and certain autoimmune diseases

Product Description:
Tretinoin CA Atra 10mg Softgel Capsules contain Tretinoin, a derivative of vitamin A, also known as all-trans retinoic acid (ATRA). This medication is used primarily in the treatment of acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia. Tretinoin works by promoting the differentiation of immature blood cells into normal cells, helping to restore normal blood cell production.

In addition to its use in treating APL, Tretinoin is also prescribed for the management of severe acne that has not responded to other treatments. It works by promoting skin cell turnover, reducing the formation of acne and unclogging pores.

Tretinoin softgel capsules are typically part of a combination therapy, particularly in APL treatment, and they are often used alongside other chemotherapy agents. Regular monitoring by a healthcare provider is essential during treatment, and it may take some time to observe the full therapeutic effects

• Kidney cancer

Rexigo 120mg tablet contains an active component called Relugolix, which belongs to a class of medicine called gonadotropin-releasing hormone (GnRH) receptor antagonists. It is used to treat adults with advanced hormone-sensitive prostate cancer.