Shree Signify Exim Private Limited

Brand Names: Truvada, Tenof-EM, Tavin-EM

Composition: Emtricitabine 200 mg, Tenofovir Disoproxil Fumarate 300 mg

Strength: Emtricitabine 200 mg, Tenofovir Disoproxil Fumarate 300 mg per tablet

Manufacturer: Various manufacturers, including Gilead Sciences, Cipla, Mylan, and Hetero.

Packaging: Typically available in bottles containing 30 tablets.

Treatment: HIV-1 infection, Pre-exposure prophylaxis (PrEP) for HIV.

Product Description:
The combination of Emtricitabine and Tenofovir Disoproxil Fumarate is a widely used antiretroviral medication that is highly effective in the treatment and prevention of HIV-1 infection. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), while Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor (NtRTI). Together, they work by inhibiting the action of reverse transcriptase, an enzyme crucial for the replication of HIV, thereby reducing the viral load in the body.

Common indications for Emtricitabine + Tenofovir Disoproxil Fumarate include:

• HIV-1 Infection: Used as part of combination antiretroviral therapy (ART) to manage and control HIV-1 infection.
• Pre-exposure Prophylaxis (PrEP): Used to reduce the risk of HIV infection in high-risk individuals when taken consistently.

Dosage and Administration:

• For Adults: One tablet (200 mg Emtricitabine + 300 mg Tenofovir Disoproxil Fumarate) taken once daily, with or without food.
• Administration: It is important to take this medication regularly and as prescribed to maintain effective drug levels in the body. Missed doses should be taken as soon as remembered unless it is close to the next scheduled dose.

Common side effects of Emtricitabine + Tenofovir Disoproxil Fumarate may include:

• Nausea
• Diarrhea
• Dizziness
• Headache
• Fatigue

Serious side effects can include kidney problems, liver issues, and a buildup of lactic acid in the blood (lactic acidosis), which requires immediate medical attention. Regular monitoring of kidney function and bone density is recommended during long-term use.

Packaging:
This combination tablet is typically packaged in bottles containing 30 tablets, which is a one-month supply.

The Emtricitabine (200 mg) + Tenofovir Disoproxil Fumarate (300 mg) tablet is a key component in the treatment and prevention of HIV, offering significant benefits in terms of reducing viral load and preventing transmission when used consistently and in combination with other antiretroviral agents.

Viropil tablet consists of the active substance called Dolutegravir, Lamivudine, Tenofovir disoproxil fumarate. Dolutegravir is an antiviral medicine belonging to the integrase inhibitor family. Lamivudine, Tenofovir disoproxil fumarate, which belongs to the antiretroviral medicine class. This medicine treats HIV (human immunodeficiency virus) infection in adults and children with 40kg or greater. It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase), which is important for virus replication. While consuming this medicine, you may still develop infections related to HIV. Although effective antiretroviral therapy reduces the risk, HIV transmission is still possible when using this medication. Contact your doctor for more information. 

Do not take Viropil tablet if you are allergic to Dolutegravir, Lamivudine, Tenofovir Disoproxil Fumarate, or its other medical ingredients. Patients diagnosed with pancreatitis or at risk of pancreatitis should take this combination of medicine cautiously. During this treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Notify your doctor if you have or had a history of lactic acidosis (excess lactic acid), pancreatitis (inflammation in the pancreas), bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B), or kidney problems. 

Inform your doctor if you are planning to get pregnant or think you may be pregnant. Breastfeeding is not recommended while taking Viropil tablet due to the potential transmission of HIV infection to the baby from mother.

• Human Immunodeficiency Virus 1 (HIV) infection in adults and children (40kg or greater).

Therapeutic Effects of Viropil Tablet 30's:

• Viropil tablet lowers HIV by inhibiting its replication. It increases the number of CD4 (T) cells, enabling the immune system to fight other infections. This lowers the risk of severity and death associated with a weak immune system.

• Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate and reduce their effectiveness by causing undesirable side effects. 

• Store at 30°C.
• Protect the medicine from light and excessive moisture.
• Keep the drug out of reach of children and pets.

• It is taken orally. Your doctor will decide the dose and duration of Viropil based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time. Do not take an additional dose to compensate for the missed dose. Do not chew, dissolve, crush, or break the tablet. 

We are the prominent exporter, wholesaler and supplier of Tenvir-Tenofovir Fumarate Tablets. Our offered range is highly demanded among clients due to its purity, optimum quality, high effectiveness and longer shelf life. Sourced from the reliable vendors in bulk quantities to fulfill the specific requirement of clients, our offered range is as per the medical industry. Moreover, we offer these tablets to our esteemed clients at industry leading prices.

• HIV infection

•  
  • HIV infection
Taficita 200mg/25mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Taficita 200mg/25mg Tablet is not a cure for HIV/AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It may also be used to prevent HIV infection in some people at high risk. It may be prescribed alone or in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. This medicine is best taken with food. Taking these medicines regularly at the right time greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include nausea, diarrhea, headache, trouble sleeping, rash, and dizziness. These are usually not serious but inform your doctor if they bother you or do not go away. It can also increase the risk of bone loss (osteoporosis) if you take it for a long time. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor. Some people put on weight while taking medicines to treat HIV/AIDS.

Before taking it, let your doctor know if you have any liver or kidney disease or bone problems. While using it, you may need regular blood tests to check your blood counts, liver function, and kidney function. Since this medicine may cause dizziness or sleepiness, do not drive if you experience these symptoms. Pregnant or breastfeeding women should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.Uses of Taficita Tablet Benefits of Taficita TabletIn HIV infectionTaficita 200mg/25mg Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.Side effects of Taficita TabletMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

• Treatment of HIV infection

Xapavir 50mg Tablet is an antiviral drug belonging to the Integrase strand transfer inhibitor category, containing the active ingredient Dolutegravir. It is used to treat human immunodeficiency virus (HIV) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken with other medicines used to treat HIV infection.

This drug is contraindicated in individuals with liver disease. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. 

It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately, and appropriate medical treatment can be initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this drug.

• Human Immunodeficiency Virus (HIV)

Therapeutic Effects of Xapavir 50mg Tablet

Xapavir 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection.

Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xapavir 50mg Tablets and reduce effectiveness by causing undesirable side effects. 

• Store Xapavir 50mg Tablet at room temperature (15°to 25°C).
• Keep the Tablet out of reach of children and pets.

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Xapavir 50mg Tablet as prescribed by your doctor. Take the Tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole Tablet with water.

• Treatment of Chronic hepatitis C virus (HCV) infection

• Fatigue
• Nausea
• Headache

Trustiva Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

Common side effects of this medicine include nausea, vomiting, diarrhea, flatulence, trouble sleeping, headache, rash, sinusitis. These are usually not serious, however, inform your doctor if they bother you or do not go away. This medicine can also make you feel dizzy or drowsy, so it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects. While on the treatment, generally, some people may experience bone pain. To cope up with this you can take calcium and vitamin D supplements as per your doctor’s advice. Birth control pills are ineffective with this medicine, therefore other reliable birth controls should be used.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or bone disease. Your doctor may suggest regular blood tests to check your blood counts, liver function, and kidney function. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

• HIV infection

• In HIV infectionTenvir-EM Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

• Hepcinat LP Tablets
• Ledifos Tablets
• Hepcvir L Tablets
• Resof L Tablets
• Lisof Tablets
• Ledviclear Tablets
• Myhep Lvir Tablets

Biktarvy is a complete HIV-1 treatment in a once-a-day single tablet containing three antiviral medicines bictegravir, emtricitabine, and tenofovir.  

Biktarvy is a complete HIV-1 treatment in a once-a-day single tablet containing three antiviral medicines bictegravir, emtricitabine, and tenofovir.  Biktarvy works by preventing HIV from multiplying in your body and lowers HIV blood levels, which decreases your chance of developing AIDS and HIV-related illnesses such as cancer or serious infections. Biktarvy is not a cure for HIV.

Twinaqt Tablet is a combination of antiretroviral medicine that contains two active substances, Dolutegravir and Lamivudine. It is indicated to treat Human Immunodeficiency Virus (HIV) in adults and adolescents over 12 who weigh at least 40 kg. HIV infection occurs when a person's immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making individuals more susceptible to opportunistic infections.

Dacihep (Daclatasvir 60mg Tablets):

• Brand Names: Dacihep, Daklinza, Mydacla
• Composition: Daclatasvir 60mg
• Strength: 60mg
• Manufacturer: Zydus Cadila, Natco Pharma, Hetero Healthcare, among others.
• Packaging: Available in blister packs of 28 tablets.
• Treatment: Used for the treatment of chronic hepatitis C infection, typically in combination with other antiviral medications.

Product Description: Dacihep (Daclatasvir 60mg Tablets) is a direct-acting antiviral (DAA) medication used in combination with other drugs, such as Sofosbuvir, to treat chronic hepatitis C virus (HCV) infection. It works by inhibiting the NS5A protein, which is essential for viral replication, thereby helping to stop the virus from multiplying in the body.

Daclatasvir is highly effective in treating genotype 1, 2, 3, and 4 strains of HCV and is a key component of several combination therapies that aim to cure the infection and prevent complications such as liver cirrhosis and liver cancer.

Dosage: The usual dose is 60mg once daily, taken orally with or without food. Dacihep is not used as a monotherapy and should be combined with other antivirals such as Sofosbuvir for a complete treatment regimen. The duration of treatment varies between 12-24 weeks, depending on the patient's genotype and other health factors.

Common Uses:

• To treat chronic hepatitis C infection in adults, particularly those with genotype 1, 2, 3, and 4 strains.
• It is often combined with Sofosbuvir and sometimes with Ribavirin to enhance effectiveness, especially in patients with cirrhosis or those who have failed prior treatment.

Side Effects: While Dacihep is generally well-tolerated, common side effects may include:

• Headache
• Fatigue
• Nausea
• Insomnia
• Diarrhea

In rare cases, more serious side effects such as bradycardia (slow heart rate) may occur when Daclatasvir is taken with Sofosbuvir and amiodarone.

Warnings:

• Contraindicated in patients with severe liver impairment without a combination therapy.
• Use with caution in patients also taking medications that affect the heart, as this combination may lead to symptomatic bradycardia.
• Drug interactions: Daclatasvir can interact with several medications, including anticonvulsants, antifungals, and certain HIV medications, which may affect its efficacy. Always consult with a healthcare provider about potential interactions.

Treatment Areas:

• Chronic Hepatitis C: To treat adult patients with chronic HCV infections, particularly genotypes 1-4, and in some cases, cirrhosis.

Dacihep (Daclatasvir) is part of a breakthrough class of direct-acting antiviral drugs that have dramatically improved cure rates for chronic hepatitis C. In combination with other antiviral medications like Sofosbuvir, it offers a well-tolerated, highly effective treatment that can lead to sustained virologic response (SVR), effectively curing most patients and significantly reducing the risk of HCV-related complications.

Product Name: Teevir Tablet

Brand Name: Teevir, Atripla, Viraday

Composition: Emtricitabine (200mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (600mg)

Manufacturer/Marketer: Mylan Pharmaceuticals Pvt Ltd - A Viatris Company

Packaging: Bottle of 30 tablets

Treatment: HIV infection

Product Description: Teevir Tablet is a combination of three antiviral medicines—Emtricitabine, Tenofovir disoproxil fumarate, and Efavirenz. It is used in the treatment of HIV infection, helping to control the virus and reduce the risk of complications such as AIDS. This medication works by preventing the virus from multiplying, thereby reducing the amount of virus in the body

Product Name: Axentri 150mg Tablet

Brand Name: Axentri, Selzentry, Celsentri

Composition: Maraviroc 150mg

Manufacturer/Marketer: Emcure Pharmaceuticals Ltd

Packaging: Box of 10 tablets

Treatment: HIV infection

Product Description: Axentri 150mg Tablet contains Maraviroc, an antiretroviral medication that blocks the CCR5 receptor on CD4 cells, preventing HIV from entering and infecting them. It is used in combination with other antiretroviral agents to manage HIV infection

Viraday Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

Common side effects of this medicine include nausea, vomiting, diarrhea, flatulence, trouble sleeping, headache, rash, sinusitis. These are usually not serious, however, inform your doctor if they bother you or do not go away. This medicine can also make you feel dizzy or drowsy, so it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects. While on the treatment, generally, some people may experience bone pain. To cope up with this you can take calcium and vitamin D supplements as per your doctor’s advice. Birth control pills are ineffective with this medicine, therefore other reliable birth controls should be used.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or bone disease. Your doctor may suggest regular blood tests to check your blood counts, liver function, and kidney function. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

• HIV infection

Product Name: Emletra Tablet

Brand Name: Emletra, Kaletra, Lopimune

Composition: Ritonavir (50mg) + Lopinavir (200mg)

Manufacturer/Marketer: Emcure Pharmaceuticals Ltd

Packaging: To be provided (specify packaging details if available)

Treatment: HIV infection

Product Description: Emletra Tablet is a combination of Ritonavir and Lopinavir, two antiretroviral medications used in the treatment of HIV infection. Ritonavir enhances the effectiveness of Lopinavir by increasing its concentration, helping to control viral load and slow the progression of the disease when used as part of combination antiretroviral therapy

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  • Brand Name: Prezista, Rezolsta, Darunax
  • Composition: Darunavir 800mg + Ritonavir 100mg
  • Manufacturer/Marketer: Cipla Ltd
  • Packaging: Box of tablets
  • Treatment: HIV infection
  • Product Description: Daruvir 800-R Tablet is a combination antiretroviral medication containing Darunavir and Ritonavir. It is used in the treatment of HIV infection by reducing the amount of HIV in the blood, helping to boost the immune system and reduce the risk of HIV-related complications. Ritonavir enhances the effect of Darunavir, making it a key drug in the management of HIV for long-term viral suppression

Daruvir 800-R Tablet

• Treatment of Chronic hepatitis C virus (HCV) infection

• Headache
• Tiredness

Brand Names: Lamivir HBV, Zeffix (widely known brand based on composition)

Composition: Lamivudine 100mg

Strength: 100mg

Manufacturer: Cipla Ltd., GlaxoSmithKline Pharmaceuticals Ltd., and other manufacturers

Packaging: 10 tablets per strip

Treatment: Chronic hepatitis B (HBV)

Product Description:
Lamivir HBV 100mg Tablet contains Lamivudine, an antiviral medication specifically used for the treatment of chronic hepatitis B (HBV). It works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the hepatitis B virus. This reduction in viral load helps to prevent the progression of liver disease associated with chronic hepatitis B, such as cirrhosis and liver cancer.

Indications for Lamivir HBV 100mg Tablet include:

• Chronic Hepatitis B: Used in patients with evidence of active viral replication and liver inflammation.

Dosage and Administration:

• The usual recommended dose for adults is 100mg once daily, taken with or without food, as prescribed by a healthcare provider.

Common side effects of Lamivir HBV 100mg Tablet may include:

• Headache
• Fatigue
• Nausea
• Diarrhea
• Abdominal pain

Patients should be closely monitored for any signs of liver function deterioration or lactic acidosis, which is a rare but serious side effect associated with Lamivudine.

Packaging:
Lamivir HBV 100mg Tablet is typically packaged in strips containing 10 tablets.

Lamivir HBV 100mg is a critical medication in managing chronic hepatitis B, helping to reduce viral load, improve liver function, and prevent complications such as cirrhosis and liver cancer.

Brand Names: Lamivir, Epivir (widely known brand based on composition)

Composition: Lamivudine 150mg

Strength: 150mg

Manufacturer: Cipla Ltd.

Packaging: 30 tablets per bottle

Treatment: HIV infection, chronic hepatitis B

Product Description:
Lamivir 150mg Tablet contains Lamivudine, an antiviral medication used primarily in the treatment of HIV (Human Immunodeficiency Virus) and chronic hepatitis B. Lamivudine works by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of HIV and hepatitis B virus, thereby reducing the viral load and slowing the progression of the disease.

Common indications for Lamivir 150mg Tablet include:

• HIV Infection: Part of antiretroviral therapy for the management of HIV-1 infection.
• Chronic Hepatitis B: Used to reduce the amount of hepatitis B virus in the body and improve liver function.

Dosage and Administration:

• The dosage of Lamivir depends on the condition being treated and the patient's overall health. Typically, for HIV infection, the recommended dose is 150mg taken twice daily, or as directed by a healthcare provider. For chronic hepatitis B, the usual dose is also 150mg once daily.

Common side effects of Lamivir 150mg Tablet may include:

• Headache
• Nausea
• Diarrhea
• Fatigue
• Dizziness

Patients should be monitored for potential side effects and any signs of lactic acidosis, which is a rare but serious condition associated with Lamivudine.

Packaging:
Lamivir 150mg Tablet is typically available in bottles containing 30 tablets.

Lamivir provides an effective option for managing HIV and chronic hepatitis B, contributing to improved outcomes and quality of life for individuals with these conditions.

Myhep Lvir contains a combination of ledipasvir and sofosbuvir. Ledipasvir and sofosbuvir are antiviral medications that prevent hepatitis C virus (HCV) cells from multiplying in your body.

To make sure Myhep Lvir is safe for you, tell your doctor if you have:

• Liver problems other than hepatitis
• Kidney disease (or if you are on dialysis)
• If you have recently used a heart rhythm medicine called amiodarone (Cordarone, Pacerone).